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Comparative Efficacy and Safety of Calcitonin Gene-Related Peptide Monoclonal Antibodies Versus Oral Gepants for Episodic Migraine Prevention: A Bayesian Network Meta-Analysis of Randomized Controlled Trials

2026-05-24

Abstract excerpt

<h4>Background: </h4> Calcitonin gene-related peptide (CGRP)-targeted therapies, including injectable monoclonal antibodies (mAbs: erenumab, fremanezumab, galcanezumab, eptinezumab) and oral gepants (atogepant, rimegepant), represent a paradigm shift in episodic migraine prevention. No direct head-to-head trials across the full drug class exist. We conducted a PRISMA-NMA-compliant Bayesian network meta-analysis (N...

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Literature Corpus work
aecf32b6-efca-5068-9837-9e5c45473aa6
DOI
10.64898/2026.05.18.26352539
Open publication

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Comparative Efficacy and Safety of Calcitonin Gene-Related Peptide Monoclonal Antibodies Versus Oral Gepants for Episodic Migraine Prevention: A Bayesian Network Meta-Analysis of Randomized Controlled TrialsDOI 10.64898/2026.05.18.26352539
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