Article

Identifying essential genes across eukaryotes by machine learning

2021-04-15

Abstract excerpt

Identifying essential genes on a genome scale is resource intensive and has been performed for only a few eukaryotes. For less studied organisms essentiality might be predicted by gene homology. However, this approach cannot be applied to non-conserved genes. Additionally, divergent essentiality information is obtained from studying single cells or whole, multi-cellular organisms, and particularly when derived fro...

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Literature Corpus work: 1a656ed0-a75d-5741-997d-e5fac7fa815d
DOI: 10.1101/2021.04.15.439934

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