Article

Highly precise breakpoint detection of chromosome balanced translocation in a Chronic Myelogenous Leukemia patient

2021-10-22

Abstract excerpt

Chronic Myelogenous Leukemia (CML) has a special phenomenon of chromosome translocation, which is called Philadelphia chromosome translocation. However, the detailed connection of this structure is troublesome and expensive to be identified. Low-coverage whole genome sequencing (LCWGS) could not only detect the chromosomal translocation which does not be known in advance, but also provide the breakpoint candidate...

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Literature Corpus work: 1a4f31f3-5f97-5a35-95ac-16264ad9214c
DOI: 10.21203/rs.3.rs-963219/v1

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