Article

HSP90/c-Myc Axis regulated by lncRNA LINC00461 upregulation inhibited the ubiquitination of c-Myc and promotes glucose Metabolism and proliferation through LDHA in Triple-negative Breast Cancer

2022-10-12

Abstract excerpt

LINC00461 represents a new long noncoding RNA. However, it is unclear whether LINC00461 is associated with glucose metabolism and proliferation in triple-negative breast cancer. Here, we show that LINC00461 overexpression induces glucose metabolism and proliferation in TNBC, whereas its downregulation markedly reduces glucose metabolism and proliferation. Mechanistically, LINC00461 might function in TNBC by bindin...

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Literature Corpus work: 1971d852-2632-5ebf-8991-f60d15d467d4
DOI: 10.21203/rs.3.rs-2134800/v1

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