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A randomized, placebo-controlled trial of a nasal spray solution containing broadly potent neutralizing antibodies against SARS-CoV-2 variants in healthy volunteers

2022-10-05

Abstract excerpt

<h4>ABSTRACT</h4> Successful COVID-19 prevention requires additional measures beyond vaccination, social distancing, and masking. A nasal spray solution containing human IgG1 antibodies against SARS-CoV-2 (COVITRAP™) was developed to strengthen other COVID-19 preventive arsenals. Here, we evaluated its pseudovirus neutralization potencies, preclinical and clinical safety profiles, and intranasal SARS-CoV-2 inhibit...

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Literature Corpus work
195dc8e4-05ac-5f14-aee0-02937c412964
DOI
10.1101/2022.10.04.22280574
Open publication

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A randomized, placebo-controlled trial of a nasal spray solution containing broadly potent neutralizing antibodies against SARS-CoV-2 variants in healthy volunteersDOI 10.1101/2022.10.04.22280574
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