Article

Efficacy and Engagement of Generative versus Retrieval-based AI conversational agents for Mental Health: A Systematic Review and Meta-Analysis

2026-05-25

Abstract excerpt

<title>Abstract</title> <p>As AI-based conversational agents (CAs) transition from rule-based logic to sophisticated generative and retrieval-based architectures, their clinical utility and long-term impact remain poorly defined. We conducted a systematic review and meta-analysis of 48 randomized controlled trials (171 effect sizes) evaluating the efficacy of AI-based CAs across psychological distress and well-be...

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Literature Corpus work: 18f69248-b65a-513f-985e-d12572fcf78f
DOI: 10.21203/rs.3.rs-9664215/v1

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