Article

Spatial and functional links between cellular virological state and progression of liver fibrosis in chronic hepatitis B

2020-01-14

Abstract excerpt

Chronic Hepatitis B Virus (HBV) infection is strongly associated with the progression of liver fibrosis, cirrhosis and hepatocellular carcinoma. Despite intensive study, the detailed mechanisms leading to HBV induced liver disease have not been fully elucidated. Previously, we reported a mosaic distribution of viral antigens and nucleic acids at single-cell level in liver tissues of chronic hepatitis B (CHB) patie...

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Literature Corpus work: 18670f7e-33f9-5f62-8edf-b83102cb0c3b
DOI: 10.1101/2020.01.13.904201

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