Article

Proteomic analysis of circulating immune cells identifies novel cellular phenotypes associated with COVID-19 severity

2022-11-18

Abstract excerpt

<h4>Summary</h4> Certain serum proteins, including CRP and D-dimer, have prognostic value in patients with SARS-CoV-2 infection. Nonetheless, these factors are non-specific, and provide limited mechanistic insight into the peripheral blood mononuclear cell (PBMC) populations which drive the pathogenesis of severe COVID-19. To identify novel cellular phenotypes associated with disease progression, we here describe...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 182909f0-16c7-5a02-a09a-8929145bdc6f
DOI: 10.1101/2022.11.16.22282338

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Proteomic analysis of circulating immune cells identifies novel cellular phenotypes associated with COVID-19 severityDOI 10.1101/2022.11.16.22282338Read

Proteomic analysis of circulating immune cells identifies cellular phenotypes associated with COVID-19 severity.Semantic proximity Read

Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection TrajectoriesSemantic proximity Read

Single-cell multi-omics analysis of the immune response in COVID-19Semantic proximity Read

Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection TrajectoriesSemantic proximity Read

The cellular immune response to COVID-19 deciphered by single cell multi-omics across three UK centresSemantic proximity Read

Identification of Distinct Immune Cells Associated with Various Clinical Presentations of COVID-19Semantic proximity Read

Single-cell multiomics revealed the dynamics of antigen presentation, immune response and T cell activation in the COVID-19 positive and recovered individualsSemantic proximity Read

A multimodal atlas of COVID-19 severity identifies hallmarks of dysregulated immunitySemantic proximity Read

Identification of Distinct Immune Cell Subsets Associated With Asymptomatic Infection, Disease Severity, and Viral Persistence in COVID-19 PatientsSemantic proximity Read

Data-driven analysis of COVID-19 reveals specific severity patterns distinct from the temporal immune responseSemantic proximity Read

Precise blood proteome profiling in an undiagnosed population with COVID-19Semantic proximity Read

Inflammation and autoreactivity define a discrete subset of patients with post-acute sequelae of COVID-19, or long-COVIDSemantic proximity Read