Article

General anesthesia dissociates discrete components of ketamine neurophysiology

2025-08-07

Abstract excerpt

<h4>Structured Abstract</h4> <h4>Importance</h4> Ketamine has well known dissociative, analgesic, and antidepressant properties, but it is unknown whether the neurophysiologic effects that are associated with these properties can be modulated separately from one another. Given prior studies that link specific cortical oscillations with specific therapeutic effects, it is likely that modulating selective aspects...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 17cdd0cb-e49c-55aa-b39f-25e842c2ea70
DOI: 10.1101/2025.08.05.25333019

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

General anesthesia dissociates discrete components of ketamine neurophysiologyDOI 10.1101/2025.08.05.25333019Read

Electroencephalographic Patterns Associated with the Pharmacokinetics and Pharmacodynamics of GABAergic Agents, Opioids, and Ketamine During General Anesthesia: A Narrative ReviewSemantic proximity Read

Ketamine can produce oscillatory dynamics by engaging mechanisms dependent on the kinetics of NMDA receptorsSemantic proximity Read

Ketamine induces multiple individually distinct whole-brain functional connectivity signaturesSemantic proximity Read

EEG signatures at different propofol vs sevoflurane concentrationsSemantic proximity Read

Mapping general anesthesia states based on electro-encephalogram transition phasesSemantic proximity Read

Immediate and Long-Term Electrophysiological Biomarkers of Antidepressant Behavioral Effects After Subanesthetic Ketamine and Medial Prefrontal Cortex Deep Brain Stimulation TreatmentSemantic proximity Read

How can I run sleep and anesthesia studies with intracranial EEG?Semantic proximity Read

Electroencephalography-Demonstrated Mechanisms of Dexmedetomidine-Mediated Deepening of Propofol Anesthesia: An Observational StudySemantic proximity Read

General anaesthesia disrupts complex cortical dynamics in response to intracranial electrical stimulation in ratsSemantic proximity Read

Propofol for treatment resistant depression: A randomized controlled trialSemantic proximity Read

Pharmacological recruitment of a VTA glutamatergic arousal circuit by the natural product BN3 drives broad-spectrum emergence from general anesthesiaSemantic proximity Read

A human intracranial map of consciousness returning from anesthesiaSemantic proximity Read