Article

Reduced YTHDF2 inhibits PD-L1 expression by stabilizing m6A-containing SPOP mRNA in colorectal cancer

2025-10-28

Abstract excerpt

<title>Abstract</title> <p> Colorectal cancer (CRC) is one of the most frequently diagnosed malignant tumors. However, clear evidence explaining the regulatory mechanisms of programmed death ligand 1 (PD-L1) in CRC has been limited. To illustrate the function of YTH N <sup>6</sup> -methyladenosine (m <sup>6</sup> A) RNA binding protein F2 (YTHDF2), we conducted a comprehensive evaluation of the expression pr...

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Literature Corpus work: 17bba1c5-8b9e-5f3f-9041-2eb9a26ef150
DOI: 10.21203/rs.3.rs-7735800/v1

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