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Chronic NaAsO2 exposure promotes migration and invasion of prostate cancer cells by Akt/GSK-3β/β-catenin/TCF4 axis-mediated epithelial-mesenchymal transition

2024-01-01

Abstract excerpt

Inorganic arsenic is a Class I human Carcinogen. However, the role of chronic inorganic arsenic exposure on prostate cancer metastasis still unclear. This study aimed to investigate the effect and mechanism of chronic NaAsO 2 exposure on migration and invasion of prostate cancer cells. DU145 and PC-3 cells were exposed to NaAsO 2 (2 µmol/L) for 25 generations. Wound healing and Transwell assays showed that chronic...

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Literature Corpus work
17164086-0d7e-59a9-a69a-d95507d33371
DOI
10.21203/rs.3.rs-3796580/v1
Open publication

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Chronic NaAsO2 exposure promotes migration and invasion of prostate cancer cells by Akt/GSK-3β/β-catenin/TCF4 axis-mediated epithelial-mesenchymal transitionDOI 10.21203/rs.3.rs-3796580/v1
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