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MDA5-autoimmunity and Interstitial Pneumonitis Contemporaneous with the COVID-19 Pandemic (MIP-C)

2023-11-05

Abstract excerpt

<h4>Background</h4> Anti-MDA5 (Melanoma differentiation-associated protein-5) positive dermatomyositis (MDA5 + -DM) is characterised by rapidly progressive interstitial lung disease (ILD) and high mortality. MDA5 senses single-stranded RNA and is a key pattern recognition receptor for the SARS-CoV-2 virus. <h4>Methods</h4> This is a retrospective observational study of a surge in MDA5 autoimmunity, as determined u...

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Literature Corpus work
16cb6ead-8500-5657-be14-59cb75214aa7
DOI
10.1101/2023.11.03.23297727
Open publication

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MDA5-autoimmunity and Interstitial Pneumonitis Contemporaneous with the COVID-19 Pandemic (MIP-C)DOI 10.1101/2023.11.03.23297727
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