Article

DOLPHIN Advances Cell Representation Beyond Gene-Level by Integrating Exon-Level Quantification and Junction Reads with Deep Neural Networks

2025-01-06

Abstract excerpt

<title>Abstract</title> <p>The advent of single-cell sequencing has revolutionized the study of cellular dynamics, providing unprecedented resolution into the molecular states and heterogeneity of individual cells. However, the rich potential of exon-level information and junction reads within single cells remains underutilized. Conventional gene-count methods overlook critical exon and junction data, limiting th...

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Literature Corpus work: 1691bd4a-66c5-5b71-b39d-7fe043c00051
DOI: 10.21203/rs.3.rs-5474597/v1

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