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Article

Spatial and temporal diversity of positive selection on shared haplotypes at the <i>PSCA</i> locus among worldwide human populations

2022-05-19

Abstract excerpt

Selection on standing genetic variation is important for rapid local genetic adaptation when the environment changes. We report that, for the prostate stem cell antigen ( PSCA ) gene, different populations have different target haplotypes, even though haplotypes are not unique to specific populations. The C-C-A haplotype, whereby the first C is located at rs2294008 of PSCA and is a low risk allele for gastric ca...

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Literature Corpus work
1668e8ab-0ccf-5113-abb1-f681ade3422b
DOI
10.1101/2022.05.19.492596
Open publication

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Spatial and temporal diversity of positive selection on shared haplotypes at the <i>PSCA</i> locus among worldwide human populationsDOI 10.1101/2022.05.19.492596
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