Article

Regeneration of Collagen Fibrils at the Papillary Dermis by Reconstructing Basement Membrane at the Dermal-Epidermal Junction

2021-07-26

Abstract excerpt

The epidermal basement membrane deteriorates with aging. We previously reported that basement membrane reconstruction not only serves to maintain epidermal stem/progenitor cells in the epidermis, but also increases collagen fibers in the papillary dermis. Here, we investigated the mechanism of the latter action. Collagen fibrils in the papillary dermis were increased in organotypic human skin culture treated with...

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Literature Corpus work: 15f30efe-0a4b-503f-ac0c-80d2b91b23a1
DOI: 10.21203/rs.3.rs-726635/v1

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