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Article

Abnormalities in the basement membrane structure promote basal keratinocytes in the epidermis of hypertrophic scars to adopt a proliferative phenotype.

International journal of molecular medicine - 1 May 2016

Yang Shaowei, Sun Yexiao, Geng Zhijun, Ma Kui, Sun Xiaoyan, Fu Xiaobing

Abstract excerpt

The majority of studies on scar formation have mainly focused on the dermis and little is known of the involvement of the epidermis. Previous research has demonstrated that the scar tissue-derived keratinocytes are different from normal cells at both the genetic and cell biological levels; however, the mechanisms responsible for the fundamental abnormalities in keratinocytes during scar development remain...

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Identifiers

PMID: 26986690
DOI: 10.3892/ijmm.2016.2519
PMCID: PMC4829134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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