Article

Endothelial Cells Promote Docetaxel Resistance of Prostate Cancer via FGF2/ERG/Akt/mTOR Signaling Pathway

2020-07-10

Abstract excerpt

<title>Abstract</title> <p>Background Docetaxel is a first-line chemotherapy for the treatment of patients with castration-resistant prostate cancer (CRPC). Despite the good initial response of docetaxel, drug resistance will inevitably occur. Mechanisms underlying docetaxel resistance are not well elaborated. Endothelial cells (ECs) have been implicated in the progression and metastasis of prostate cancer (PCa)...

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Literature Corpus work: 15a5f67b-d22d-5ea4-b8be-2a8105aa250d
DOI: 10.21203/rs.3.rs-40867/v1

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