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Protein Disulfide Isomerase 4 Drives Docetaxel Resistance in Prostate Cancer

1 Jan 2020

Abstract excerpt

BACKGROUND: Protein disulfide isomerase 4 (PDIA4) has been reported to be closely associated with chemoresistance in several types of malignancies. But the pathogenic mechanisms of PDIA4 involved in docetaxel (DTX) resistance in prostate cancer (PCa) are still unknown. Hence, this study was conducted to evaluate the potential effect of PDIA4 on chemoresistance to DTX in PCa cells and to investigate the underlying...

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PMID: 33238278
DOI: 10.1159/000511505

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