Article

Protocol for expediting drug targets search in S . Typhi through subtractive genomics and the identification of lead-based novel small molecules

2022-10-12

Abstract excerpt

Typhoid fever is transmitted by ingestion of polluted water, contaminated food, and stool of typhoid-infected individuals, mostly in developing countries with poor hygienic environments. To find novel therapeutic targets and inhibitors, the complete genomes of eight Salmonella Typhi strains were primarily subjected to the EDGAR tool to predict the core genome (n=3207). Human non-homology (n=2450) was followed by...

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Literature Corpus work: 15a38acb-8e53-5003-b9f7-ed36bfd61f04
DOI: 10.22541/au.166556193.32446071/v1

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