Article

Understanding developmental decision making in malaria parasites using single-cell transcriptomics

2020-01-01

Abstract excerpt

Single-cell sequencing has the potential to revolutionise our understanding of malaria parasites. Malaria is caused by single-celled parasitic organisms of the genus Plasmodium which display remarkable cellular plasticity during their complex life cycle with large variations in size (1.2 to 50 μm) and the environments they inhabit in mammalian and mosquito hosts. Clinical symptoms of malaria result from asexual re...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1561242e-8da9-5ae2-9b3d-6b4a19137431
DOI: 10.17863/cam.66721

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Understanding developmental decision making in malaria parasites using single-cell transcriptomicsDOI 10.17863/cam.66721Read

Single-Cell Transcriptomics To Define Plasmodium falciparum Stage Transition in the Mosquito MidgutSemantic proximity Read

A single-cell atlas of Plasmodium falciparum transmission through the mosquitoSemantic proximity Read

A single-cell atlas of <i>Plasmodium falciparum</i> transmission through the mosquitoSemantic proximity Read

The Malaria Cell Atlas: Single parasite transcriptomes across the complete Plasmodium life cycleSemantic proximity Read

The Malaria Cell Atlas: a comprehensive reference of single parasite transcriptomes across the complete <i>Plasmodium</i> life cycleSemantic proximity Read

Single-cell RNA-seq reveals hidden transcriptional variation in malaria parasites.Semantic proximity Read

Probing Plasmodium falciparum sexual commitment at the single-cell levelSemantic proximity Read

Latent transcriptional variations of individual Plasmodium falciparum uncovered by single-cell RNA-seq and fluorescence imagingSemantic proximity Read

Single cell RNA-sequencing identifies the gene expression profile of the asexual and sexual invasive merozoites of the human malaria parasiteSemantic proximity Read

Single-cell transcriptomics to define <i>Plasmodium falciparum</i> stage-transition in the mosquito midgutSemantic proximity Read

Single-cell RNA sequencing of Plasmodium vivax sporozoites reveals stage- and species-specific transcriptomic signaturesSemantic proximity Read

Exploring parasite heterogeneity using single-cell RNA-seq reveals a gene signature among sexual stage Plasmodium falciparum parasitesSemantic proximity Read