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Article

Single-cell RNA-seq reveals hidden transcriptional variation in malaria parasites.

eLife - 27 Mar 2018

Reid Adam J, Talman Arthur M, Bennett Hayley M, Gomes Ana R, Sanders Mandy J, Illingworth Christopher J R, Billker Oliver, Berriman Matthew, Lawniczak Mara Kn

Abstract excerpt

Single-cell RNA-sequencing is revolutionising our understanding of seemingly homogeneous cell populations but has not yet been widely applied to single-celled organisms. Transcriptional variation in unicellular malaria parasites from the Plasmodium genus is associated with critical phenotypes including red blood cell invasion and immune evasion, yet transcriptional variation at an individual parasite level has...

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Identifiers

PMID: 29580379
DOI: 10.7554/eLife.33105
PMCID: PMC5871331

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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