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Article

PPAR /RXR Heterodimers Control Human Trophoblast Invasion

1 Oct 2001

Abstract excerpt

The ligand-dependent nuclear receptors PPARgamma and RXRalpha/beta were recently determined to be essential for murine placental development and trophoblast differentiation. In the current study we examined the expression and role of the PPARgamma/RXRalpha heterodimers in human invasive trophoblasts. We first report that in human first trimester placenta, PPARgamma and RXRalpha are highly expressed in...

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Identifiers

PMID: 11600579
DOI: 10.1210/jc.86.10.5017

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