Article
When and How Ferroptosis Becomes Pathogenetic in Psoriasis
2026-02-26
Abstract excerpt
Psoriasis is classically framed as an IL-23/IL-17/TNF-driven immune disease, yet durable remission remains elusive for many patients, suggesting that epidermal-intrinsic pathogenic mechanisms shape chronicity and therapeutic escape. Here we propose ferroptosis, viewed as iron-dependent membrane lipid peroxidation coupled to failure of lipid repair, as a unifying, epidermis-centered axis that links metabolic stress...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 14022b06-4d9c-5615-af15-a459551884dd
- DOI
- 10.20944/preprints202602.1713.v1