Article

The role of mitochondrial dysfunction in acute pancreatitis

2010-01-01

Abstract excerpt

Acute pancreatitis is a serious and often lethal inflammatory disease. Its causes are diverse and incompletely understood; however, gallstones and alcohol abuse are the principal triggers. Oxidative stress has been proposed as a determinant of acute pancreatitis (AP) severity, and has been the subject of recent clinical trials. The major AP precipitants, alcohol, alcohol metabolites and bile salts, were investigat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1334a8cb-6a02-57f3-b9bf-0407646d2355
DOI: 10.17638/00001488

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The role of mitochondrial dysfunction in acute pancreatitisDOI 10.17638/00001488Read

The effects of mitochondria-targeted antioxidant mitoquinone on pancreatic acinar cellsSemantic proximity Read

Alcohol-induced pancreatic injury.Semantic proximity Read

Oxidative stress alters mitochondrial bioenergetics and modifies pancreatic cell death independently of cyclophilin D, resulting in an apoptosis-to-necrosis shiftSemantic proximity Read

Molecular mechanisms of pancreatitis: current opinion.Semantic proximity Read

Role of alcohol metabolism in chronic pancreatitis.Semantic proximity Read

Pathophysiology of alcoholic pancreatitis: An overviewSemantic proximity Read

Susceptibility Factors and Cellular Mechanisms Underlying Alcoholic Pancreatitis.Semantic proximity Read

The involvement of Receptor Interacting Protein Kinase 1 (RIPK1) in the pathogenesis of acute pancreatitisSemantic proximity Read

Impaired autophagosome-lysosome fusion in the pathogenesis of pancreatitisSemantic proximity Read

Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models.Semantic proximity Read

The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injurySemantic proximity Read

Xanthine Oxidase: A Longstanding Target in Acute Pancreatitis with New WaysSemantic proximity Read