Article

Joint embedding of biological networks for cross-species functional alignment

2022-01-20

Abstract excerpt

<h4>ABSTRACT</h4> Model organisms are widely used to better understand the molecular causes of human disease. While sequence similarity greatly aids this transfer, sequence similarity does not imply functional similarity, and thus, several current approaches incorporate protein-protein interactions (PPIs) to help map findings between species. Existing transfer methods either formulate the alignment problem as a m...

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Identifiers and source

Literature Corpus work: 129627da-ba7c-5d96-a1a7-c1658e371a3c
DOI: 10.1101/2022.01.17.476697

Open publication

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