Article
Genetic study of pediatric hypertrophic cardiomyopathy in Egypt.
Cardiology in the young - 1 Dec 2020
Darwish Rania K, Haghighi Alireza, Seliem Zeinab S, El-Saiedi Sonia A, Radwan Nora H, El-Gayar Dina F, Elfeel Nesrine S, Abouelhoda Mohamed, Mehaney Dina A
Abstract excerpt
Paediatric cardiomyopathy is a progressive and often lethal disorder and the most common cause of heart failure in children. Despite their severe outcomes, their genetic etiology is still poorly characterised. The current study aimed at uncovering the genetic background of idiopathic primary hypertrophic cardiomyopathy in a cohort of Egyptian children using targeted next-generation sequencing. The study included...
Topics
- Adolescent
- Cardiomyopathy, Hypertrophic
- Child
- Child, Preschool
- Egypt
- Female
- Genetic Testing
- High-Throughput Nucleotide Sequencing
- Humans
- Male
- Mutation