Article

A Novel Computational Machine Learning Pipeline to Quantify Similarities in Three-Dimensional Protein Structures

2024-08-17

Abstract excerpt

Animal models are widely used during drug development. The selection of suitable animal model relies on various factors such as target biology, animal resource availability and legacy species. It is imperative that the selected animal species exhibit the highest resemblance to human, in terms of target biology as well as the similarity in the target protein. The current practice to address cross-species protein si...

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Literature Corpus work: 11cf07c7-ff65-5b0a-9e1e-c059818d99d9
DOI: 10.1101/2024.08.14.607969

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