Article

Multi-omic characterization of human sural nerves across polyneuropathies

2024-12-10

Abstract excerpt

Diseases of peripheral nerves termed polyneuropathies (PNPs) are common, mechanistically heterogeneous, and challenging to diagnose. Here, we integrated single nuclei transcriptomics of peripheral nerves from 33 human PNP patients and four controls (365,708 nuclei) with subcellular spatial transcriptomics. We identified novel and human-specific nerve cell type markers including unexpectedly heterogeneous perineuri...

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Literature Corpus work: 11beabcb-5312-5957-9777-fcc9db45fb08
DOI: 10.1101/2024.12.05.627043

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