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Association between NUDT15 rs116855232T/C Genetic Polymorphism and Mercaptopurine Toxicity in Syrian Children with Acute Lymphoblastic Leukemia

2024-01-31

Abstract excerpt

<h4>Purpose: </h4> NUDT15 genetic polymorphism is known to be associated with frequent hematopoietic toxicities during acute lymphoblastic leukemia (ALL) mercaptopurine therapy. The aim of this study is to test this association in a group of Syrian children with ALL, in addition to quantify the prevalence of the corresponding SNP in patient population. Patients and Methods: This is a retrospective study that inclu...

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Literature Corpus work
1141022e-976c-5297-a99b-ed1c2f1c54f3
DOI
10.22541/au.170667311.14903431/v1
Open publication

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