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A topographic lung cell atlas reveals regional variation in cell-type specific gene programs and identifies healthy and diseased cellular neighborhoods

2024-10-07

Abstract excerpt

<title>Abstract</title> <p>Integration of single cell mRNA sequencing data from millions of cells revealed a high diversity of cell types in the healthy and diseased human lung. In a large and complex organ, which is also constantly exposed to external agents, it is crucial to understand the influence of lung tissue topography or external factors on gene expression variability within each cell type. Here, we appl...

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Literature Corpus work
112cce44-0485-5c11-932c-74c5033755ca
DOI
10.21203/rs.3.rs-5046381/v1
Open publication

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A topographic lung cell atlas reveals regional variation in cell-type specific gene programs and identifies healthy and diseased cellular neighborhoodsDOI 10.21203/rs.3.rs-5046381/v1
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