Article

Effect of B7-H4 downregulation induced by Toxoplasma gondii infection on dysfunction of decidual macrophages contributes to adverse pregnancy outcomes

2022-09-27

Abstract excerpt

<h4>Background: </h4> Toxoplasma gondii（T. gondii） infection during pregnancy can lead to fetal defect or congenital complications. The inhibitory molecule B7-H4 expressed on decidual macrophage (dMφ) exerted important role in maternal-fetal tolerance. However, the effect of B7-H4 on the function of dMφ during T. gondii infection remains unclear. <h4>Methods:</h4> In the present study, the change of B7-H4 expressi...

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Literature Corpus work: 10c85ce3-45a4-53b5-a8e7-8f3bb9049a35
DOI: 10.21203/rs.3.rs-2092665/v1

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