Article

Predictive features of gene expression variation reveal a mechanistic link between expression variation and differential expression

2020-02-11

Abstract excerpt

For most biological processes, organisms must respond to extrinsic cues, while maintaining essential gene expression programs. Although studied extensively in single cells, it is still unclear how variation is controlled in multicellular organisms. Here, we used a machine-learning approach to identify genomic features that are predictive of genes with high versus low variation in their expression across individual...

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Literature Corpus work: 1084ffbe-fd38-5936-aa0f-e9268e400f2b
DOI: 10.1101/2020.02.10.942276

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