Article

Deciphering the Regulatory Symphony: MicroRNA Orchestration of the RAS/MAPK Signaling Pathway and its Interplay across Cellular Networks in Colorectal Cancer Tumorigenesis

2024-02-28

Abstract excerpt

The RAS/MAP kinase pathway, pivotal in cancer development, intertwines with microRNAs (miRNAs), shaping CRC's dynamic cellular landscape. This study utilizes a systems biology approach, employing advanced bioinformatics tools to unravel miRNA-mediated regulatory networks in CRC. Investigating miRNA dysregulation, identifying hub genes, and exploring interplay between signaling pathways aim to provide nuanced insig...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0fe06113-6d73-5ba4-8a65-7cab0e48cee3
DOI: 10.21203/rs.3.rs-3990461/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Deciphering the Regulatory Symphony: MicroRNA Orchestration of the RAS/MAPK Signaling Pathway and its Interplay across Cellular Networks in Colorectal Cancer TumorigenesisDOI 10.21203/rs.3.rs-3990461/v1Read

The potential role of regulatory microRNAs of RAS/MAPK signaling pathway in the pathogenesis of colorectal cancerSemantic proximity Read

Integrative analyses of molecular pathways and key candidate biomarkers associated with colorectal cancerSemantic proximity Read

Transcriptomic Signatures in Colorectal Cancer ProgressionSemantic proximity Read

Colorectal cancer (CRC) as a multifactorial disease and its causal correlations with multiple signaling pathwaysSemantic proximity Read

Charting the molecular links between driver and susceptibility genes in colorectal cancer.Semantic proximity Read

Differential expression analysis of genes and long non-coding RNAs associated with KRAS mutation in colorectal cancer cells.Semantic proximity Read

Identification of hub genes and potential molecular mechanisms in MSS/MSI classifier primary colorectal cancer based on multiple datasetsSemantic proximity Read

Identification of Hub genes with prognostic values in colorectal cancer by integrated bioinformatics analysis.Semantic proximity Read

Hub Genes and Key Pathway Identification in Colorectal Cancer Based on Bioinformatic AnalysisSemantic proximity Read

Identification of key pathways and genes in mutant KRAS colorectal cancer by integrated bioinformatics analysis.Semantic proximity Read

Integrated bioinformatics approach to unwind key genes and pathways involved in colorectal cancerSemantic proximity Read

Identification of key genes and pathways involved in microsatellite instability in colorectal cancerSemantic proximity Read