Article

Testis Cell Pyroptosis Mediated by CASP1 and CASP4: Possible Sertoli Cell-Only Syndrome Pathogenesis

2023-01-31

Abstract excerpt

<h4>Background: </h4> and aims: Sertoli cell-only syndrome (SCOS) is the most serious pathological type of non-obstructive azoospermia. In recent years, some genes related to SCOS have been identified, including FANCM, TEX14, NR5A1, NANOS2, PLK4, WNK3, and FANCA, but they cannot explain the pathogenesis of SCOS completely. This study attempted to explain the spermatogenesis dysfunction in SCOS through testicular t...

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Literature Corpus work: 0fc3604c-e2a8-520c-af34-fa8883f1c83b
DOI: 10.21203/rs.3.rs-2495066/v1

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