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Response to anti-angiogenic therapy is affected by AIMP protein family activity in glioblastoma and lower-grade gliomas

2025-03-14

Abstract excerpt

<h4>Background</h4> Glioblastoma (GBM) is a highly vascularized, heterogeneous tumor, yet anti-angiogenic therapies have yielded limited survival benefits. The lack of validated predictive biomarkers for treatment response stratification remains a major challenge. Aminoacyl tRNA synthetase complex-interacting multicomplex proteins (AIMPs) 1/2/3 have been implicated in CNS diseases, but their roles in gliomas rema...

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Literature Corpus work
0fb7a7ca-69cd-5d5d-8fe3-aeeb4140ef0f
DOI
10.1101/2025.03.13.643116
Open publication

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Response to anti-angiogenic therapy is affected by AIMP protein family activity in glioblastoma and lower-grade gliomasDOI 10.1101/2025.03.13.643116
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