Deciphering hub genes as potential therapeutic target involved in progression of Glioblastoma multiforme disease: A multi-omics approach

Abstract excerpt

<title>Abstract</title> <p>Glioblastoma multiforme (GBM) is a highly aggressive primary brain tumor associated with high fatality rates, poor prognosis, and limited treatment options. To enhance our understanding of the disease and pave the way for targeted therapies, it is imperative to identify key genes influencing GBM progression. In this study, we harnessed RNA-Seq gene count data from GBM patients sourced f...

Topics

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• Bioinformatics and Genomic Networks
• Cancer, Hypoxia, and Metabolism
• Chemokine receptors and signaling
• Ferroptosis and cancer prognosis
• Gene expression and cancer classification
• Glioma Diagnosis and Treatment
• Immune cells in cancer
• Neuroinflammation and Neurodegeneration Mechanisms

Identifiers and source

Literature Corpus work

ebcbf68a-e5c5-5c61-96b3-5ea19b9b1c94

DOI

10.21203/rs.3.rs-4620933/v1