Article

Patient-Specific Adaptations in ERAS for High-Altitude Laparoscopic Cholecystectomy: The PAERS Hypothesis

2026-08-25

Abstract excerpt

<h4>Background: </h4> ERAS protocols reduce hospital stay by 1.88 days and complications by 29% globally, but their one-size-fits-all paradigm, validated at sea level, may fail at high altitude where chronic hypoxia and population-specific genetic adaptations remodel baseline physiology. No study has quantified ERAS effect weight shifts at high altitude or proposed a theoretical model to explain the gap. <h4>Objec...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0f7207b9-195a-5961-b891-3e48ea9409fb
DOI: 10.64898/2026.08.21.26360905

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Patient-Specific Adaptations in ERAS for High-Altitude Laparoscopic Cholecystectomy: The PAERS HypothesisDOI 10.64898/2026.08.21.26360905Read

DNA methylation in adaptation to high-altitude environments and pathogenesis of related diseasesSemantic proximity Read

Causal Relationships Between High-Altitude Adaptation, Metabolic Traits, and Tumors: Insights from Mendelian Randomization.Semantic proximity Read

Altitude hypoxia and hypoxemia: pathogenesis and management.Semantic proximity Read

Does Chronological Age Misclassify Perioperative Risk? A Prospective Multicenter Cohort Study Using Frailty and Handgrip StrengthSemantic proximity Read

Using Mendelian Randomization to Dissect the Relationship Between High-Altitude Adaptation and Liver Diseases/Traits.Semantic proximity Read

DNA Methylation Changes and Phenotypic Adaptations Induced Repeated Extreme Altitude Exposure at 8848 Meters.Semantic proximity Read

Chronic Mountain Sickness: Clinical Aspects, Etiology, Management, and Treatment.Semantic proximity Read

Innate Immune Phenotypes During Acute High-Altitude Exposure.Semantic proximity Read

Impact of high altitude on the incidence of postoperative venous thromboembolism and its genetic susceptibility: A meta-analysis and systematic review.Semantic proximity Read

Design and conduct of Xtreme Everest 2: An observational cohort study of Sherpa and lowlander responses to graduated hypobaric hypoxiaSemantic proximity Read

Glucocorticoid Programming of Erythrocyte Hypoxic Memory Enables Rapid High-Altitude AcclimatizationSemantic proximity Read

EPAS1 and VEGFA gene variants are related to the symptoms of acute mountain sickness in Chinese Han population: a cross-sectional study.Semantic proximity Read