Article

Granulocyte Derived Resistin Inhibits Monocyte Maturation and Induces Immune Suppression in CMML

2025-03-07

Abstract excerpt

Chronic myelomonocytic leukaemia (CMML) is a haematological malignancy characterised by overlapping myeloid dysplasia and proliferation with persisting monocytosis. While monocytes are the cardinal malignant cell type in CMML, as a stem cell neoplasm the disease clone comprises most lineages and differentiation stages, including granulocytes. To investigate the pathogenic contribution of granulocytes in CMML maint...

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Literature Corpus work: 0f2fc286-9bae-50d4-80ad-7e58388e9e76
DOI: 10.1101/2025.03.03.640303

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