Article

Drug combinations with apoptosis pathway targeted agents alrizomadlin, pelcitoclax, and dasminapant in multi-cell type tumor spheroids

2024-06-14

Abstract excerpt

<h4>ABSTRACT</h4> Apoptosis, or programmed cell death, plays a critical role in maintaining tissue homeostasis by eliminating damaged or abnormal cells. Dysregulation of apoptosis pathways is a hallmark of cancer, allowing malignant cells to evade cell death and proliferate uncontrollably. Targeting apoptosis pathways has emerged as a promising therapeutic strategy in cancer treatment, aiming to restore the balan...

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Literature Corpus work: 0f006338-8e81-531e-bb2f-7cb7d0d892eb
DOI: 10.1101/2024.06.11.598557

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