Effect of progesterone on <i>Candida albicans</i> biofilm formation under acidic conditions: a transcriptomic analysis

Abstract excerpt

Vulvovaginal candidiasis (VVC) caused by Candida albicans is a common disease worldwide. A very important C. albicans virulence factor is its ability to form biofilms on epithelium and/or on intrauterine devices promoting VVC. It has been shown that VVC has a hormonal dependency and that progesterone affects virulence traits of C. albicans cells. To understand how the acidic environment (pH 4) and progesterone...

Topics

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• Antifungal resistance and susceptibility
• Bacterial biofilms and quorum sensing
• Fungal Infections and Studies
• Legionella and Acanthamoeba research
• Oral microbiology and periodontitis research
• Probiotics and Fermented Foods
• Reproductive tract infections research
• Urinary Tract Infections Management

Identifiers and source

Literature Corpus work

0ecd025e-0892-5529-9f4a-be2d1b450462

DOI

10.1101/591347