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Article

Molecular association of Candida albicans and vulvovaginal candidiasis: focusing on a solution

13 Oct 2023

Abstract excerpt

Candida albicans-mediated vulvovaginal candidiasis (VVC) is a significant challenge in clinical settings, owing to the inefficacy of current antifungals in modulating virulence, development of resistance, and poor penetration into the biofilm matrix. Various predisposition factors are molecular drivers that lead to the dysbiosis of normal microflora of the vagina, upregulation of central metabolic pathways,...

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PMID: 37900321
DOI: 10.3389/fcimb.2023.1245808

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