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Biofilm matrix regulation by Candida glabrata Zap1 under acidic conditions: transcriptomic and proteomic analyses

4 Nov 2024

Abstract excerpt

ABSTRACT The vaginal acidic environment potentiates the formation of Candida glabrata biofilms, leading to complicated and recurrent infections. Importantly, the production of matrix is known to contribute to the recalcitrant features of Candida biofilms. In this study, we reveal that Zap1 regulates the matrix of C. glabrata acidic biofilms and analyzed the modulation of their transcriptome (by microarrays) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39494883
DOI: 10.1128/spectrum.01201-24

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