Article

Network Adaptability Governs Resilience and Susceptibility to Social Defeat

2025-12-01

Abstract excerpt

<h4>ABSTRACT</h4> Stress resilience is defined as the ability to maintain mental health after adversity. In humans, resilience is marked by threat–safety discrimination and extinction of fear, whereas susceptibility involves fear generalization and extinction resistance. Using a translational mouse model of chronic social defeat stress combined with preregistered multimodal brain imaging, we investigated structur...

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Literature Corpus work: 0e68eee8-4251-5757-8d68-f58c9fd3630c
DOI: 10.1101/2025.11.26.690729

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