Article

Vascular Endothelial Growth Factors and Angiopoietins As New Players in Mastocytosis

2021-02-04

Abstract excerpt

<title>Abstract</title> <p>Mastocytosis is a disorder characterized by the abnormal proliferation and/or accumulation of mast cells in different organs. More than 90% of patients with systemic mastocytosis have a gain-of-function mutation in codon 816 of the KIT receptor on mast cells (MCs). The symptoms of mastocytosis patients are related to the MC-derived mediators that exert local and distant effects. MCs pro...

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Literature Corpus work: 0e5db6f3-f76f-5565-9224-8ccf98c35bb4
DOI: 10.21203/rs.3.rs-163383/v1

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