Article
De-repression of Transposable Elements by Histone Hyperacetylation Leads to Sterile Inflammation in Preeclampsia
2025-03-26
Abstract excerpt
<title>Abstract</title> <p>Preeclampsia is a pregnancy-associated hypertension disorder that affects 5–10% of pregnant women each year, resulting in adverse outcomes for both mother and child. Although the pathophysiology of preeclampsia remains somewhat unclear, it is linked to inflammation, senescence, and accelerated ageing phenotypes. Here, we aimed to investigate the altered epigenetic and transcriptomic cha...
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Identifiers and source
- Literature Corpus work
- 0e4e7fc9-0ff7-5e30-9f07-1543e2005e80
- DOI
- 10.21203/rs.3.rs-6121510/v1