Article

The Biorepository and Integrative Genomics resource for inclusive genomics: insights from a diverse pediatric and admixed cohort

2025-01-03

Abstract excerpt

The Biorepository and Integrative Genomics (BIG) Initiative in Tennessee has developed a pioneering resource to address gaps in genomic research by linking genomic, phenotypic, and environmental data from a diverse Mid-South population, including underrepresented groups. We analyzed 13,152 exomes from BIG and found significant genetic diversity, with 50% of participants inferred to have non-European or several typ...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0e1e1485-f8ad-518d-99f6-1c68436d398e
DOI: 10.1101/2025.01.03.25319944

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Biorepository and Integrative Genomics resource for inclusive genomics: insights from a diverse pediatric and admixed cohortDOI 10.1101/2025.01.03.25319944Read

Sequencing and health data resource of children of African ancestrySemantic proximity Read

Sequencing and health data resource of children of African ancestry.Semantic proximity Read

Rare coding variant analysis for human diseases across biobanks and ancestries.Semantic proximity Read

Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations.Semantic proximity Read

Decoding Genetics, Ancestry, and Geospatial Context for Precision HealthSemantic proximity Read

The frequency of pathogenic variation in the All of Us cohort reveals ancestry-driven disparitiesSemantic proximity Read

Towards a fine-scale population health monitoring systemSemantic proximity Read

Public RNA-seq data are not representative of global human diversitySemantic proximity Read

The frequency of pathogenic variation in the All of Us cohort reveals ancestry-driven disparities.Semantic proximity Read

Subcontinental Genetic Diversity in the <i>All of Us</i> Research Program: Implications for Biomedical ResearchSemantic proximity Read

Diverse Genomes, Shared Health: Insights from a Health System BiobankSemantic proximity Read

Human genetics. The genetics of Mexico recapitulates Native American substructure and affects biomedical traits.Semantic proximity Read