Genetics and context for precision health in Greater Boston.

doi:10.1038/s41467-025-66598-8

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Article

Genetics and context for precision health in Greater Boston.

Nature communications - 26 Nov 2025

Koyama Satoshi, Wang Ying, Paruchuri Kaavya, Uddin Md Mesbah, Cho So Mi J, Urbut Sarah M, Sui Yang, Fahed Akl C, Kamineni Himani, Haidermota Sara, Hornsby Whitney E, Green Robert C, Daly Mark J, Neale Benjamin M, Ellinor Patrick T, Smoller Jordan W, Slaugenhaupt Susan A, Lebo Matthew S, Karlson Elizabeth W, Martin Alicia R, Natarajan Pradeep

Abstract excerpt

Mass General Brigham, an integrated healthcare system based in the Greater Boston area of Massachusetts, annually serves 1.5 million patients. We established the Mass General Brigham Biobank (MGBB), currently encompassing 142,238 participants, to unravel the intricate relationships among genomic profiles, environmental context, and disease manifestations within clinical practice. In this manuscript, we described...

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PMID: 41298473
DOI: 10.1038/s41467-025-66598-8
PMCID: PMC12749686

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