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Research on the identification of collagen-related genes in osteoporosis based on transcriptome data and multi-omics analysis, and validation of biomarkers

2026-05-25

Abstract excerpt

<title>Abstract</title> <p>Osteoporosis (OP) links to bone collagen loss, but the role of collagen-related genes (CRGs) is unclear. We aimed to screen OP-related CRGs as potential diagnostic and therapeutic targets. By integrating transcriptome data from public databases and employing differential expression analysis, consensus clustering, protein-protein interaction analysis, and the Boruta machine learning algo...

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Literature Corpus work: 0dd97aef-6a0d-58db-915b-b6c96b2d1c28
DOI: 10.21203/rs.3.rs-8976862/v1

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