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Identification of the transcriptome signatures and immune-inflammatory responses in postmenopausal osteoporosis

12 Dec 2023

Abstract excerpt

Postmenopausal osteoporosis is the most common type of osteoporosis in women. To date, little is known about their transcriptome signatures, although biomarkers from peripheral blood mononuclear cells are attractive for postmenopausal osteoporosis diagnoses. Here, we performed bulk RNA sequencing of 206 samples (124 postmenopausal osteoporosis and 82 normal samples) and described the clinical phenotypic...

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PMID: 38187229
DOI: 10.1016/j.heliyon.2023.e23675

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