Article

The Discovery of Breast Cancer Risk Gene and Establishment of Prediction Model Based on Estrogen Metabolism Regulation

2020-09-29

Abstract excerpt

<title>Abstract</title> <p>Background In this study, we aim to uncover the relationship between estrogen levels and the genetic polymorphism of estrogen metabolism-related enzymes with breast cancer (BC) and establish a risk prediction model based on polygenic risk score. Methods Unrelated BC patients and healthy subjects were recruited for analysis of the estrogen levels and the single nucleotide polymorphisms...

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Literature Corpus work: 0dbb9ee2-2e69-5d0d-a083-7e84666e5fc6
DOI: 10.21203/rs.3.rs-50139/v1

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